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Pharmaceutical Antitumor Powder Altretamine For Anti-Cancer CAS 645-05-6

Categories Pharmaceutical Raw Materials
Brand Name: JNJG
Model Number: 99%
Certification: USP BP SGS KOSHER
Place of Origin: CHINA
MOQ: Negotiable
Price: negotiation
Payment Terms: TT, Money Gram, Western Union, Bitcoin
Supply Ability: 1000kg in stock
Delivery Time: within 12 hours after you payment
Packaging Details: 1kg/ foil bag or as your requirement
CAS: 645-05-6
Assay: 99%
Package: 25kg/drum
Standard: enterprise Standard
Appearance: White powder
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    Pharmaceutical Antitumor Powder Altretamine For Anti-Cancer CAS 645-05-6

    Pharmaceutical Raw Powder Altretamine For Anti-Cancer CAS 645-05-6


    Quck details

    Product name

    Altretamine


    Synonym

    1,3,5-Triazine-2,4,6-triamine,1,3,5-tris

    (dimethylamino) -s-triazine;2,4,6-Tris (Dimethylamino)-s-triazine;Aitretamine;


    CAS

    645-05-6


    MF

    C9H18N6


    MW

    210.28


    Assay

    99%


    Package

    25kg/drum


    Standard

    enterprise Standard


    Usage

    An antitumor agent which also acts as a chemosterilant for male houseflies and other insects. Antineoplastic.


    MOQ

    10g




    Mechanism


    The precise mechanism by which altretamine exerts its anti-cancer effect is unknown but it is classified by MeSH as an alkylating antineoplastic agent. This unique structure is believed to damage tumor cells through the production of the weakly alkylating species formaldehyde, a product of CYP450-mediated N-demethylation. Administered orally, altretamine is extensively metabolized on first pass, producing primarily mono- and didemethylated metabolites. Additional demethylation reactions occur in tumor cells, releasing formaldehyde in situ before the drug is excreted in the urine.


    The carbinolamine (methylol) intermediates of CYP450-mediated metabolism also can generate electrophilic iminium species that are capable of reacting covalently with DNA guanine andcytosine residues as well as protein. Iminium-mediated DNA cross-linking and DNA-protein interstrand cross-linking, mediated through both the iminium intermediate and formaldehyde, have been demonstrated, although the significance of DNA cross-linking on altretamine antitumor activity is uncertain.



    Specifications


    1. Licensed manufacturer
    2. 15 years production experience
    3. Perfect quality
    4. Competitive price


    Research & Development


    We have a highly qualified and experienced R&D team for research, development, pilot test, commercialized scale production and product registration.


    Our Advantages


    1. packaging & delivery. We do have professional team for package and shipment.Special & safe way to ship all the products to the destination country no matter the quantity or location.Fast and discreet shipment can be arranged for customs clearance guaranteed, security is the key& we do have reshipping policy.


    2. our advantages


    We are back to introduce us to more clients again! Actually, we are in the business as a professional raw material lab supplier for over 15 years, we have more than enough experience to handle everything in the right way.


    a. Our products did & do be shipped safely to many countries with mass quantity always.


    b. We do get professional team, esp., for package & shipment, do have strong connection in shipping system, all the parcels are sent via traceable couriersas UPS, FedEx, DHL & so on, do offer customs clearance guaranteed to the destination country.


    c. Products are in prompt stock, chargeable samples are available at any time,can be shipped out

    immediately upon the requirement.


    d. You get the absolutely right choice if want the best stuff & service, high quality,good price, fast and safety delivery guaranteed, we do have reshipping policy once anyuncontrollable incident happen


    Quality Pharmaceutical Antitumor Powder Altretamine For Anti-Cancer CAS 645-05-6 for sale
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